Bacterial Capsules And The Development Of Pneumonia Case Study

Question Description

From April 3 to April 24, 2001, nine cases of pneumonia occurred in elderly residents (median age of 86 years) living at a long-term care facility in New Jersey. Seven of the nine patients had Streptococcus pneumoniae isolated from blood cultures, with capsular serotyping revealing that all isolates were serotype 14 and of the same clonal group. Seven of the nine patients also lived in the same wing of the nursing home. The two patients that were culture negative did contain gram-positive diplococci in their sputum and had chest X-rays consistent with pneumonia. Epidemiological studies of the patients and controls revealed that all who developed pneumonia had no documented record of vaccination with the pneumococcal polysaccharide vaccine (PPV). In contrast, about 50% of the controls were vaccinated with PPV. Even though other risk factors were assessed, the lack of vaccination with PPV was the only one strongly associated with illness. Unfortunately, despite treatment, four of the nine patients with pneumonia died.

Once the outbreak was recognized, PPV was offered to those 55 residents who had not yet been vaccinated: 37 of these were vaccinated, whereas the other 18 were either ineligible or refused the vaccine. Other control measures included refusal to admit patients without a history of PPV vaccine.

 –    What special advantage does the capsule confer on the pathogen Streptococcus pneumoniae?

–    Why are those who have been vaccinated against Streptococcus pneumoniae more resistant to infection by this agent?

Cowan, M. K. (2014) (4th Ed.). Microbiology: A Systems Approach, McGraw Hill

Get 20% Discount on The assignment
Pages (550 words)
Approximate price: -

Try it now!

Get 20% Discount on The Assignment

We'll send you the first draft for approval by at
Total price:
$0.00

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

EssayBrill has stood as the world’s leading custom essay writing services providers. Once you enter all the details in the order form under the place order button, the rest is up to us.

Essays

Essay Writing Services

At EssayBrill, we prioritize on all aspects that bring about a good grade such as impeccable grammar, proper structure, zero-plagiarism and conformance to guidelines. Our experienced team of writers will help you completed your essays and other assignments.

Admissions

Admission and Business Papers

Be assured that you’ll definitely get accepted to the Master’s level program at any university once you enter all the details in the order form. We won’t leave you here; we will also help you secure a good position in your aspired workplace by creating an outstanding resume or portfolio once you place an order.

Editing

Editing and Proofreading

Our skilled editing and writing team will help you restructure you paper, paraphrase, correct grammar and replace plagiarized sections on your paper just on time. The service is geared toward eliminating any mistakes and rather enhancing better quality.

Coursework

Technical papers

We have writers in almost all fields including the most technical fields. You don’t have to worry about the complexity of your paper. Simply enter as much details as possible in the place order section.